RUMORED BUZZ ON FLUDARABINE

Research have revealed that knockdown of ULK inhibits autophagosome formation. Mice with defects in ULK1 and ULK2 die inside of 24 h after beginning [41]. When ULK1 is expressed in mammalian cells, ULK2 is not necessary for autophagy. On the other hand, when ULK1 expression is inhibited, ULK2 can compensate with the purpose of ULK1 in regulating au